Microbial mechanisms of tolerance to weak acids: an overview

[摘要] Carboxylic acids are ubiquitous molecules found in microbial metabolic pathways and that have been explored for a wide array of applications including food preservation (e.g., acetic, propionic, benzoic, and sorbic acids), chemotherapy (e.g., the analgesic acetylsalicylic acid, the immunosuppressor mycophenolic acid or the antimalarial drugs artesunic and artemisinic acids) or agriculture (e.g., the herbicides 2,4-dichlorophenoxyacetic acid). This Research Topic contributes to the understanding of the molecular mechanisms underlying adaptation to weak acid stress in microbes, a knowledge base that impacts the fields of Medicine, Health, Food Safety and the Environment.

[学科分类] 微生物学和免疫学

[关键词] Carboxylic Acids;weak acid food preservatives;Response and resistance to weak acid stress;food-borne spoilage microbes;tolerance to weak acids