Institutions, public policy and the product life cycle : the globalization of biomanufacturing and implications for Massachusetts

[摘要] (cont.) This thesis argues that in advanced manufacturing industries such as biotech manufacturing, it is precisely innovation that brings this complex manufacturing activity to high-skilled, high-wage, technologically advanced regions of the world. This research examines the geographic evolution of biomanufacturing and finds that product life cycle theory provides an excellent model for understanding the dynamics of the industry, albeit with some twists which add to the richness of the literature. These twists are first, the role that institutions, specifically regulation, play in shaping the product life cycle by providing patents that slow the entry of competition. Second, public policy, specifically competitive international tax policy, has become a new differentiator between countries that are seeking to attract high value-added, high-wage manufacturing through the use of tax incentives. Tax-Advantaged Locations (TALs) have become the new low cost destination for advanced manufacturing despite their high wages and costs. Through interviews with 47 biomanufacturing executives and analysis of the geography of biomanufacturing investments made by 96 companies between 2002 and 2013, I find that technologically advanced regions such as Massachusetts retain the most innovative aspects of the industry, including early stage manufacturing as well as the first stage of commercial manufacturing. Massachusetts has a significant opportunity to retain and grow the industry, though the economic development impact is not in a large number of jobs, but in the building of a ;;regional system of innovation;; based in human capital and companies that can usher in new technologies and emerging industries.

[发布机构] Massachusetts Institute of Technology