已收录 272983 条政策
 政策提纲
  • 暂无提纲
The SirT3 Divining Rod Points to Oxidative Stress
[摘要] Sirtuins are NAD+ dependent deacetylases that counter aging and diseases of aging. Sirtuin research has focused on SirT1, which deacetylates transcription factors and cofactors in the nucleus. More recent findings highlight SirT3 as a mitochondrial sirtuin that regulates metabolism and oxidative stress. This review focuses on new data linking SirT3 to management of reactive oxygen species from mitochondria, which may have profound implications for aging and late-onset diseases.
[发布日期]  [发布机构] Elsevier
[效力级别]  [学科分类] 
[关键词]  [时效性] 
   浏览次数:3      统一登录查看全文      激活码登录查看全文