Partial Hepatectomy Achievement by New Device in Rabbits Model

[摘要] This study was to evaluate the efficiency of new device (heat gun) for liver surgery. This instrument is firstly introduce to the surgery to control bleeding during tissue dissection.Eighteen rabbits aged between 3-4 months weighted between 1.5- 2 kg from both sex were used in this experiment. The rabbits were divided into three groups. First group (A) underwent partial hepatectomy by heat gun to posterior left lobe of liver and second group (B) underwent partial hepatectomy by using suturing of severed posterior left lobe of liver served as positive control . The third group (C) underwent laprotomy only and served as negative control.Postoperative examination of physiological parameters was measured for 3 postoperative days, The animal were scarified after 7, 15, 21 days after operation for gross and histopathological examination.The results revealed that efficiency of heat gun for partial hepatectomy and it was a fast method and prevented bleeding from the incision site and it is decreased time that needed for suturing hepatic incision in liver surgery.The physiological parameters in all the experimental rabbits were within normal range during the three days following the operations, and they gained their normal body activities and food intake.In gross pathological examination there is no serious complication that recorded except adhesion with omentum that is considered advantage for sealing incision and preventing adhesion with other neighboring viscera and prevent possible bleeding from hepatic incision. In histopathology the rabbits in group (A) show faster regeneration than in group (B).In conclusion, the heat gun is effective device for partial hepatectomy rabbits models and It is the first use for this purpose in this animals.

[学科分类] 土木及结构工程学

[关键词] Partial Hepatectomy;Heat gun;suture;Histopathology;Gross pathology;Rabbits