Heterotopic salivary gland tissue in the gastro-oesophageal junction: a rare entity

[摘要] Introduction: Gastric and pancreatic heterotopia are the two most common types of heterotopiasseen in the gastrointestinal tract (GIT). These are the two most common types of heterotopias seen inthe oesophagus as well. The occurrence of heterotopic salivary gland tissue (HSGT) in the GIT is rare,and most reported cases are colorectal and anal lesions with only a few cases involving theoesophagus.Case report: A 69-year-old man presented with a seven-month history of gastro-oesophageal refluxdisease (GORD). The upper gastrointestinal endoscopy showed a moderate hiatus hernia with a palepink mucosal patch close to the gastro-oesophageal junction. The biopsy showed oesophageal tissuewith morphological changes of mild reflux oesophagitis. The submucosal tissue contained organizedglandular structures with mucinous glands and intercalated ducts resembling mature salivary glandtissue. There was no evidence of Barrett oesophagus, dysplasia or neoplasm.Discussion and conclusion: HSGT is most commonly seen in the head and neck region of the body,and its occurrence in the GIT is rare. Occurrence of oesophageal HSGT is extremely rare and mostcases have presented with symptoms of GORD. Although HSGT is usually benign and a rarephenomenon, clinicians and pathologists need to be aware of this condition to prevent a delay indiagnosis and inappropriate management.

[学科分类] 生理学与病理学

[关键词] heterotopia;salivary gland tissue;oesophagus