Prognostic impact of circulating tumor cells in patients with soft-tissue sarcomas: a prospective study

[摘要] Sarcomas represent a heterogenous group of tumorsaccounting for about 1% of cancer in adults and 15% inchildren [1]. However, despite adequate locoregional treatment, up to 40% of patients develop metastatic disease.Drugs used in the advanced setting have very limited efficacy, with a response rate of <10% and progression-freesurvival of <4 months and are mainly used for palliative purposes [1]. It is, therefore, important to monitorindividual therapy responses to avoid inefficient therapyand unnecessary toxicity. Such monitoring is currentlybased on repeated CT imaging which may represent animportant burden for patients with advanced disease [2].

[学科分类] 社会科学、人文和艺术（综合）