Weakened humoral immune responses of inactivated SARS-CoV-2 vaccines in patients with solid tumors

[摘要] Coronavirus disease 19 (COVID-19), caused by severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2),remains a pandemic. Cancer patients have a higher riskof poor outcomes for SARS-CoV-2 infection than the general population [1]. Vaccines were shown to effectivelyprevent SARS-CoV-2 infection, severe disease progression,and mortality. Inactivated SARS-CoV-2 vaccines (BBIBPCorV and CoronaVac) have been approved and widelyused in China, with the former shown to be more effective than the latter [2]. Hence, there is an urgent need toinvestigate the safety and humoral immune responses ofinactivated vaccines in cancer patients.

[学科分类] 社会科学、人文和艺术（综合）