Treatment of Congenital Melanocytic Nevi With a Dual-Wavelengths Copper Vapor Laser: A Case Series

[摘要] Introduction: Congenital melanocytic nevus (CMN) is a severe challenge for dermatology. Thispigmented skin lesion is undesirable for patients because of its localization in open areas of thebody. Various visible and near-infrared laser systems and intense pulsed light (IPL) sources havebeen applied for CMN treatment. However, post-traumatic hyperpigmentation, structural changes,atrophy, and scarring due to non-specific thermal damage have been observed. Many patients haveshown recurrence after treatment. Therefore, it highlights the need for testing new laser modalitiesfor the management of CMN.Methods: Two adult II Fitzpatrick phototype patients (a 55-year-old male and a 30-year-old female)with middle-sized facial CMN (on the forehead and lower eyelid) are presented. All patients weretreated with dual-wavelength copper vapor laser (CVL) radiation at 511 nm and 578 nm wavelengthswith a power ratio of 3:2. The average power was 0.7-0.85 W with an exposure time of 0.3 seconds.The spot size amounted to 1 mm.Results: Both patients showed complete resolution of CMN after CVL treatments. CMN becamecrusted within a few days after the laser treatment and peeled off within seven days. No recurrenceswere observed during the follow-up period up to 24 months.Conclusion: The middle-sized CMN can be successfully treated with dual-wavelength CVL radiation.

[学科分类] 基础医学

[关键词] Copper vapor laser;Melanocytic nevi;Selective pigmented treatment;Computersimulation;Blood vessel;Hyperpigmentation