Metabolic Syndrome In Light Of Five Different Definitions.

[摘要] Metabolic syndrome (MetS) is a worldwide epidemic, It is known for its complex etiology. MetS is asyndrome and its definition includes a cluster of etiologically related factors that have a direct effect to increasethe risk of coronary heart disease (CHD), other atherosclerotic cardiovascular diseases (CVD), and type II diabetesmellitus (DM Type-II). Core manifestations of the syndrome are abdominal obesity and/or insulin resistance (IR).Recently, many additional factors besides those traditionally used to define MetS have been identified to beassociated with MetS. Currently, Several different definitions of MetS exist at present, which cause a significantconfusion as to whether they identify the same individuals or not. There are substantial confusions related to theprevalence trend, relation with age, sex, obesity, hypertension. In this review, we critically compared the existingdefinitions and discussed the trends related to prevalence, relation with age, sex, obesity and hypertension. Weconclude that there is still a need to develop uniform criteria to define MetS, and further work to understandassociation of MetS with obesity to better identify patients at risk and there is a need of early marker to diagnoseand treat MetS before the complications develop fully.

[学科分类] 工程和技术（综合）

[关键词] MetS;metabolic syndrome;epidemic.