Pemphigus and bullous pemphigoid

[摘要] Pemphigus and bullous pemphigoid are distinct autoimmune blistering diseases that are characterised by the presence of autoantibodies directed against specific adhesion molecules of the skin and mucous membranes. The comparison and contrast of molecular mechanism of blister formation of these two diseases provide a rational diagnostic and therapeutic approach to affected patients.

[关键词] FOLIACEUS FOGO SELVAGEM;PARANEOPLASTIC PEMPHIGUS;VULGARIS ANTIGEN;EXTRACELLULAR DOMAIN;NEONATAL MICE;CELL-ADHESION;SKIN DISEASES;AUTOANTIBODIES;ACANTHOLYSIS;BACULOVIRUS