Electron microscopic observations of the developing mouse eye: I. Basement membranes during early development and lens formation
[摘要] Astudywascarriedoutoncertainultrastructuralfeaturesofthedevelopmentoftheopticandlenticularprimordiaofthemouseembryowithrelationtocertainfeaturesofadulteye.Itwasobservedthatabasementmembranecompletelyenclosesboththeopticandlenticularprimordiafromtheirbeginningsandthatthisboundingfeaturepersistsintheadult.Twobasementmembranes,thoseoftheectodermandopticcup,separatetheopposingtissuesatthesiteofpossiblelensinduction.Thesebasementmembranesmaybecontinuouswithoneanotherattheanteriorneuropore.Basementmembranesarewelldefinedonneuroectodermalstructuresbeforebeingobservableonnearbybloodvessels.Theectodermalbasementmembraneexistspriortolensformation.Thefirstofthelenscapsulelaminaemaybeidenticalwiththisbasementmembrane.Lenscapsulelaminationisalreadymultipleat12daysofgestation.Theseparationofthelensfromtheectodermhastheappearanceofaconstrictionprocessinwhichaclearzoneofcytolysisdefinestheseparationplane.Bothcellandbasementmembranesattheperipheryofthiszoneseemtoinfold.Thelocationofterminalbarsintheadulteyelikewiseparallelstheembryonicsituation.Somepreliminaryobservationsofembryoniccellsandtheirinclusionsarealsoreported.Smallparticleswereoccasionalfeaturesoftheopticcupandectodermalongtheirzoneofapproximation.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
