AN APPARENT CONNECTION BETWEEN HISTIDINE, RECOMBINATION, AND REPAIR IN NEUROSPORA

[摘要] Two mutants of Neurospora crassa, uvs-3 and mei-3 , share four properties—UV sensitivity, inhibition by histidine, meiotic blockage when homozygous, and increased duplication instability (due to mitotic crossing over, to deletions or to both). The present paper shows that a third nonallelic mutant, uvs-6 , exhibits the same four properties.—Also, the instability of duplications in the absence of any UV-sensitive mutant is increased by the presence of histidine in the growth medium.

[学科分类] 医学（综合）