Evaluation of anti-inflammatory potential of various parts of Ptersospermumcanescens, Roxb., (Sterculiaceae) extracts in experimental animals.

[摘要] Inflammation and oxidative stress are features of many degenerative diseases. In this present study, the petroleum ether, chloroform and methanol extracts (100 mg/kg, 200 mg/kg) of Pterospermum canescens, Roxb., (Sterculiaceae) plant extracts (leaves, stem and stem bark) was investigated for its anti-inflammatory activity. Carrageenan induced paw oedema method in Wistar Albino rats were used in this study to assess anti-inflammatory potential of the plant using Indomethacin as standard (10 μg/kg). Petroleum ether, chloroform and methanol extracts of leaf, stem and stem bark were exhibited significant (P < 0.001) anti-inflammatory activity at 100 mg/kg and 200 mg/kg doses when compared with the standard, Indomethacin.

[学科分类] 药理学