CTP can replace GTP in reactions catalyzed by eukaryotic peptide elongation factor 1

[摘要]

In several reactions catalyzed by highly purified peptide elongation factor 1 from rabbit reticulocytes, GTP may be fully replaced by CTP but not by ATP or UTP. This holds true for the factor-dependent binding of aminoacyl-tRNA to ribosomes, GTPase activity, GTP-dependent autophosphorylation of the factor protein and binding of cholesteryl 14-methylhexadecanoate by the factor.

[学科分类] 生物化学/生物物理

[关键词] CTP;GTP;Peptide elongation factor 1;GTPase;Autocatalytic phosphorylation Cholesteryl 14-methylhexadecanoate