Effects of Oil Adjuvant on Systemic Response to Escherichia coli Lipopolysaccharide in Swine

[摘要] References(11)Intramuscular injection of 0.1 mg/kg of Escherichia coli lipopolysaccharide (LPS) mixed with Freund's complete adjuvant (LPS+FCA) in piglets mititated the leukopenia and TNF-α and cortisol levels in the serum compared with that of LPS suspended in LPS-free saline. The endotoxin level in the serum of the LPS+FCA was remarkably reduced. These results suggest that the addition of oil adjuvant mitigate the systemic toxicity of LPS.

[学科分类] 兽医学

[关键词] LPS;oil adjuvant;swine