Validation of an automated sleep spindle detection method for mouse electroencephalography

[摘要] Study ObjectivesSleep spindles are abnormal in several neuropsychiatric conditions and have been implicated in associated cognitive symptoms. Accordingly, there is growing interest in elucidating the pathophysiology behind spindle abnormalities using rodent models of such disorders. However, whether sleep spindles can reliably be detected in mouse electroencephalography (EEG) is controversial necessitating careful validation of spindle detection and analysis techniques.

[学科分类] 生理学

[关键词] automated spindle detection;mouse electroencephalography;polysomnography;sigma;model species;psychiatry