0014 Genome-Wide Association Study of Sleep Latency in Drosophila melanogaster

[摘要] IntroductionOne of the hallmarks of insomnia in humans is difficulty initiating sleep. Sleep latency, the amount of time it takes to fall asleep initially, is one way to quantify this difficulty. Sleep latency can be easily measured in flies as the time to the fly’s first night sleep bout. In this study, we leveraged raw sleep and activity data from a previous genome-wide association study (GWAS) of Drosophila melanogaster. Our goal was to assess the extent of genetic variation in sleep latency in a wild-derived population of flies and to identify polymorphic variants explaining that variation.

[学科分类] 生理学