0001 The Innervation Of Hypoglossal Motoneurons That Originates From A7 And/or Subcoeruleus Noradrenergic Neurons Is Impaired In Mice Treated With Chronic Intermittent Hypoxia

[摘要] IntroductionNoradrenergic (NA) neurons of A7 and SubCoeruleus (SubC) pontine nuclei project to the hypoglossal (XII) nucleus and provide excitatory input to XII motoneurons that play a role in the pathology of obstructive sleep apnea (OSA). We sought to investigate whether chronic intermittent hypoxia (CIH), one of the major morbid factors of OSA, affects the NA innervation of XII motoneurons that originates from A7 and SubC neurons.

[学科分类] 生理学