Local inhibition of 5-lipoxygenase enhances bone formation in a rat model

[摘要] ObjectivesRecent studies have shown that modulating inflammation-related lipid signalling after a bone fracture can accelerate healing in animal models. Specifically, decreasing 5-lipoxygenase (5-LO) activity during fracture healing increases cyclooxygena

[学科分类] 骨科学

[关键词] Bone regeneration;5-lipoxygenase;A-79175;Rat;Femoral defect;Bone formation