Long term effects of cilostazol in a dog with sick sinussyndrome

[摘要] Sick sinus syndrome (SSS) is a type of bradyarrhythmia that can lead to syncope.Cilostazol has been reported to be an effective treatment for human patients with SSS andother bradyarrhythmias. This report describes the successful long-term treatment withcilostazol in a dog with SSS. A nine-year old intact male Miniature Schnauzer presentedwith a history of syncopal episodes and unsteady gait. After cilostazol treatment, thetotal heart rate (HR), mean HR, and frequency of premature ventricular contractions (PVCs)increased, while the maximum HR and maximum pause time decreased. Additionally, the numberof syncopal episodes decreased. The dog died suddenly, 1,418 days after the start ofcilostazol treatment. Cilostazol may be a useful therapeutic agent in canines withSSS.

[学科分类] 兽医学

[关键词] cilostazol;dog;sick sinus syndrome